Probabilistic graphical models for genetic association studies

New probabilistic graphical models for genetic regulatory networks studies

This paper introduces two new probabilistic graphical models for reconstruction of genetic regulatory networks using DNA microarray data. One is an independence graph (IG) model with either a forward or a backward search algorithm and the other one is a Gaussian network (GN) model with a novel greedy search method. The performances of both models were evaluated on four MAPK pathways in yeast an...

Probabilistic Graphical Models

P Probabilistic Graphical Models

Bayesian network (BN) A directed graph whose nodes represent variables, and edges represent influences. Together with conditional probability distributions, a Bayesian network represents the joint probability distribution of its variables. Conditional probability distribution Assignment of probabilities to all instances of a set of variables when the value of one or more variables is known. Con...

Visualizing Graphical Probabilistic Models

Complex probabilistic models are difficult to evaluate not only for consistency with the domain theory but also for novelty and significance. In this paper we describe the current visual representations of Bayesian networks and then present an implementation containing enhancements to these visualizations by integrating several well known techniques. We then apply our approach in an exploration...

Probabilistic Graphical Models

This report1 presents probabilistic graphical models that are based on imprecise probabilities using a comprehensive language. In particular, the discussion is focused on credal networks and discrete domains. It describes the building blocks of credal networks, algorithms to perform inference, and discusses on complexity results and related work. The goal is to present an easy-to-follow introdu...